Imidamide (amidine) analogs that can inhibit the activity of sphingosine kinase 1 and sphingosine kinase 2 (SphKl & SphK2) are provided. The compounds can prevent angiogenesis in tumors.
申请公布号
WO2011020116(A1)
申请公布日期
2011.02.17
申请号
WO2010US45660
申请日期
2010.08.16
申请人
UNIVERSITY OF VIRGINIA PATENT FOUNDATION;LYNCH, KEVIN, R.;MACDONALD, TIMOTHY, L.;MATHEWS, THOMAS, P.;KENNEDY, ANDREW;KHAREL, YUGESH
