发明名称 |
METHODS EMPLOYING INSECT MODELS FOR DETERMINING INTESTINAL ABSORPTION OF CHEMICAL COMPOUNDS |
摘要 |
There is provided insect screening models to determine gastrointestinal absorption of different chemical compounds in vertebrates, and in particular humans, in order to improve the compound screening procedures/processes in the early drug discovery process. This offers many advantages relative to prior technologies since insect models are more reliable tools for the decision-making process than the existing in vitro models, and will speed up the drug screening process and reduce the late phase attrition rate. Moreover, it will reduce the number of mammals sacrificed during the drug discovery phase. |
申请公布号 |
WO2011018449(A1) |
申请公布日期 |
2011.02.17 |
申请号 |
WO2010EP61590 |
申请日期 |
2010.08.10 |
申请人 |
ENTOMOPHARM APS;AADAL NIELSEN, PETER;ANDERSSON, GUNNAR;ANDERSSON, OLGA |
发明人 |
AADAL NIELSEN, PETER;ANDERSSON, GUNNAR;ANDERSSON, OLGA |
分类号 |
G01N33/50 |
主分类号 |
G01N33/50 |
代理机构 |
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代理人 |
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主权项 |
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地址 |
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