摘要 |
<p><P>PROBLEM TO BE SOLVED: To provide a fused protein which can specifically inhibit an autoantibody and can effectively prevent or treat autoantibody autoimmune diseases. <P>SOLUTION: The fused protein is characterized by comprising, a protein (X) and a protein (A), wherein the protein (X) comprises a segment which can be recognized by an autoantibody that causes autoantibody autoimmune diseases and the protein (A) comprises a fragment of an antibody heavy-chain constant region. The fused protein is produced by mutually binding a DNA encoding the protein (X) to a DNA encoding the protein (A), inserting the obtained DNA into an expression vector, and transducing the vector into a host cell to express the fused protein. <P>COPYRIGHT: (C)2011,JPO&INPIT</p> |