发明名称 |
Preparation of biodegradable microparticles containing a biologically active agent |
摘要 |
<p>A process for preparing biodegradable microparticles comprising a biodegradable polymeric binder and a biologically active agent. A first phase, comprising the active agent and the polymer, and a second phase are combined under the influence of mixing means to form an emulsion and microparticles are isolated from the emulsion. A blend of at least two substantially non-toxic solvents, free of halogenated hydrocarbons, is used to dissolve or disperse the agent and dissolve the polymer.</p> |
申请公布号 |
EP2283821(A1) |
申请公布日期 |
2011.02.16 |
申请号 |
EP20100176953 |
申请日期 |
1994.11.18 |
申请人 |
ALKERMES, INC. |
发明人 |
RAMSTACK, MICHAEL J.;HERBERT, PAUL F.;STROBEL, JAN;ATKINS, THOMAS J. |
分类号 |
A61K9/16;A61K9/50;A61K31/519;A61K31/568;A61K31/57;A61K47/34;B01J13/02;B01J13/06;B01J13/08 |
主分类号 |
A61K9/16 |
代理机构 |
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代理人 |
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主权项 |
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地址 |
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