发明名称 STRAINS OF ESCHERICHIA COLI MODIFIED BY METABOLIC ENGINEERING TO PRODUCE CHEMICAL COMPOUNDS FROM HYDROLYZED LIGNOCELLULOSE, PENTOSES, HEXOSES AND OTHER CARBON SOURCES.
摘要 The present invention relates to novel strains of Escherichia coli known as CL3, JU15, JU15A, LL26, MS04 and derivatives that preferentially produce metabolites, particularly D-lactate, L-lactate and also ethanol, in a high yield and with high selectivity, from a variety of carbon sources, such as: xylose-rich culture media (a main carbon source), particularly media formulated with hydrolysates of vegetable fibres, such as sugar cane, agave and fodder bagasse, in addition to a wide variety of agro-industrial waste, such as milk whey or forest, cellulose, fodder or shrub waste, and, in general, any lignocellulose-derived material. These strains make use of the production of the metabolite of interest (in particular, D-lactate, L-lactate or ethanol) as sole route for regenerating the reducing power of the microorganism. The invention also relates to fermentation methods for producing said metabolites from media with diverse carbon sources, including glucose, lactose or xylose.
申请公布号 MX2009008453(A) 申请公布日期 2011.02.16
申请号 MX20090008453 申请日期 2009.08.07
申请人 UNIVERSIDAD NACIONAL AUTA NOMA DE MA XICO 发明人 GUILLERMO GOSSET LAGARDA;ALFREDO MARTA NEZ JIMA NEZ;GEORGINA TERESA HERNA NDEZ CHA VEZ;GERARDO HUERTA BERISTAIN;BERENICE TRUJILLO MARTA NEZ;JOSA UTRILLA CARRERI
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