| 发明名称 |
METHODS OF DIAGNOSING, PREVENTING AND TREATING BONE MASS DISEASES |
| 摘要 |
<p>The present invention provides methods and therapeutic agents for lowering or increasing serum serotonin levels in a patient in order to increase or decrease bone mass, respectively. In preferred embodiments, the patient is known to have, or to be at risk for, a low bone mass disease such as osteoporosis and the agents are TPH1 inhibitors or serotonin receptor antagonists.</p> |
| 申请公布号 |
EP2282756(A1) |
申请公布日期 |
2011.02.16 |
| 申请号 |
EP20090728672 |
申请日期 |
2009.03.30 |
| 申请人 |
THE TRUSTEES OF COLUMBIA UNIVERSITY IN THE CITY OF NEW YORK |
发明人 |
KARSENTY, GERARD;DUCY, PATRICIA, F.;XIE, YULI;LANDRY, DONALD;YADAV, VIJAY |
| 分类号 |
A61K31/357;A61K31/513;A61K45/06;A61P19/08;A61P19/10 |
主分类号 |
A61K31/357 |
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