5-FLUORO-3ALPHA ,17BETA-DIHYDROXY-5ALPHA-ANDROSTAN-6-ONE, THE METHOD FOR ITS PRODUCTION AND ITS USE FOR INFLUENCING PLANT GROWTH

摘要

5-Fluoro-3a,17ß-dihydroxy-5a-androstan-6-one IV and the method of its production are described. The synthesis consists of partial hydrolyses of 5-fluoro-6-oxo-5a-androstan-3ß,17ß-diyl diacetate with mild alkaline agent to 5-fluoro-3ß-hydroxy-6-oxo-5a-androstan-17ß-yl acetate that on solvolytic change of hydroxyl configuration in position 3 affords 5-fluoro-3a-hydroxy-6-oxo-5a-androstan-17ß-yl acetate, which on deprotection afforded desired 5-fluoro-3a,17ß-dihydroxy-5a-androstan-6-one IV. The invention relates also to the use of 5-fluoro-3a,17ß-dihydroxy-5a-androstaii-6-one IV for influencing of plant growth, especially for increasing of plant yield and also for removal of plant stresses.