发明名称 |
Selective androgen receptor modulators and methods of use thereof |
摘要 |
<p>This invention provides a novel class of androgen receptor targeting agents (ARTA). The agents define a new subclass of compounds which are tissue-selective androgen receptor modulators (SARM), which are useful for in treating, preventing, suppressing, inhibiting or reducing the incidence of osteoporosis. These agents have an unexpected in-vivo activity for an androgenic and anabolic activity of a nonsteroidal ligand for the androgen receptor. These agents may be active alone or in combination with progestins or estrogens.</p> |
申请公布号 |
EP2284149(A1) |
申请公布日期 |
2011.02.16 |
申请号 |
EP20100182881 |
申请日期 |
2001.08.23 |
申请人 |
UNIVERSITY OF TENNESSEE RESEARCH FOUNDATION |
发明人 |
DALTON, JAMES;MILLER, DUANE, D.;YIN, DONGHUA;HE, YALI |
分类号 |
A61P5/28;C07C233/15;A61K31/167;A61K31/404;A61K31/4706;A61K31/661;A61P7/06;A61P13/08;A61P15/00;A61P15/08;A61P15/16;A61P19/10;A61P35/00;C07C233/33;C07C233/48;C07C235/24;C07C235/26;C07C237/14;C07D209/08;C07D215/22;C07D215/227;C07D271/12;G01N33/543;G01N33/74 |
主分类号 |
A61P5/28 |
代理机构 |
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代理人 |
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主权项 |
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地址 |
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