发明名称 3-HETEROARYL-3,5-DIHYDRO-4-OXO-4H-PYRIDAZINO[4,5-B]INDOLE-1-ACETAMIDE DERIVATIVES, THEIR PREPARATION AND THEIR APPLICATION IN THERAPEUTICS
摘要 The invention relates to compounds of general formula (I), (see above formula) where X = H, or halogen, R1 = H, or (C1-C4)alkyl, R2 and R3 independently = H or a(C1-C4) alkyl group, or R2 and R3 form, together with the nitrogen atom carrying them, a pyrrolidinyl, piperidinyl, morpholino or 4-(C1-C4)alkylpiperazinyl group and Het = a heteroaromatic group, being a pyridinyl, quinolinyl, isoquinolinyl, pyrimidinyl, pyrazinyl or pyridazinyl group, the heteroaromatic group optionally having one or several halogen atoms and/or one or several (C1-C4) alkyl, (C1-C4)alkoxy groups as substituents, in the base state, as addition salts with acids, solvates or hydrates, pharmaceutical compositions comprising the above, methods for production thereof and synthetic intermediates thereof.
申请公布号 CA2481460(C) 申请公布日期 2011.02.15
申请号 CA20032481460 申请日期 2003.04.02
申请人 SANOFI-AVENTIS 发明人 FROISSANT, JACQUES;MARABOUT, BENOIT;MARGUET, FRANK;PUECH, FREDERIC
分类号 C07D487/04;A61K31/5025;A61K31/503;A61K31/5377;A61P3/10;A61P9/00;A61P9/04;A61P9/08;A61P9/10;A61P13/12;A61P17/00;A61P17/04;A61P17/06;A61P25/00;A61P29/00;A61P35/00;A61P37/02;C07D;C07D209/00;C07D209/18;C07D209/42;C07D241/00;C07D487/02 主分类号 C07D487/04
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