发明名称 Oxazoloisoquinoline derivatives as thrombin receptor antagonists
摘要 This application provides for oxazolisoquinoline derivatives of the formula or a pharmaceutically acceptable salt of said compound wherein: B is —CH═CH—; M is —C(R1)(R2)—; and the remaining substituents are as defined in the specification as well as pharmaceutical compositions containing them and a method of treating diseases associated with thrombosis, atherosclerosis, restenosis, hypertension, angina pectoris, arrhythmia, heart failure, and cancer by administering said compounds. This application also provides for combination therapy with the compounds of Ib or pharmaceutically acceptable salts thereof with other cardiovascular agents.
申请公布号 US7888369(B2) 申请公布日期 2011.02.15
申请号 US20060642170 申请日期 2006.12.20
申请人 SCHERING CORPORATION 发明人 CHACKALAMANNIL SAMUEL;WANG YUGUANG
分类号 C07D491/14;A61K31/4355;A61P7/02;A61P9/00;A61P9/02;A61P9/06;A61P9/10;A61P9/12 主分类号 C07D491/14
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