| 摘要 |
PURPOSE: A method for manufacturing allyl benzene derivatives is provided to be applied in the synthesis of various natural products, to prepare allyl benzene derivatives at high yield compared with a conventional allyl indium reaction, and to compensate toxicity of organic tin compound. CONSTITUTION: A method for manufacturing allyl benzene derivatives comprises the steps of: reacting an allyl derivative represented by chemical formula 2, indium halide represented by chemical formula 3, amine compound represented by chemical formula 4, in the indium, palladium catalyst, and ligand condition to prepare allyl indium represented by chemical formula 5; performing cross coupling reaction of the allyl indium with an allyl compound represented by chemical formula 6 to prepare an allyl benzene derivative represented by chemical formula 1. |
