发明名称 COMPOUNDS AND COMPOSITIONS AS PROTEIN KINASE INHIBITORS
摘要 The invention provides novel pyrimidine derivatives and pharmaceutical compositions thereof, and methods for using such compounds. For example, the pyrimidine derivatives of the invention may be used to treat, ameliorate or prevent a condition which responds to inhibition of anaplastic lymphoma kinase (ALK) activity, c-ros oncogene (ROS), insulin-like growth factor (IGF-1R), and/or insulin receptor (InsR) or a combination thereof.
申请公布号 KR20110015414(A) 申请公布日期 2011.02.15
申请号 KR20107024933 申请日期 2009.04.03
申请人 IRM LLC;NOVARTIS AG 发明人 CHEN BEI;JIANG TAO;MARSILJE THOMAS H. III;MICHELLYS PIERRE YVES;NGUYEN TRUC NGOC;PEI WEI;WU BAOGEN;GAO ZHAOBO;GE YONGHUI;HUANG CHEN;LI YUNCHENG;ZHU XUEFENG
分类号 C07D401/12;A61K31/506;A61P35/00;C07D401/14 主分类号 C07D401/12
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