发明名称 N-cyano-formamidines
摘要 New N-cyano-formamidine are disclosed of the formula I: <IMAGE> I wherein R is 2-[[(5-methyl-1H-Imidazol-4-yl)methyl]thio]ethyl, 2-[[[5-[dimethylamino)methyl]-2-furanyl]methyl]thio]ethyl, 2-[[[2-[(aminoiminomethyl)amino]-4-thiazolyl]methyl]thio]ethyl or 3-[3-(1-piperidinylmethyl)phenoxy]propyl, as well as a process for its production, and pharmaceutical preparations containing the same. The compounds possess histamine-induced gastric acid secretion-inhibiting activity, and are indicated for use in the treatment of peptic ulcer and other pathologies caused or stimulated by gastric acidity.
申请公布号 US4600780(A) 申请公布日期 1986.07.15
申请号 US19840595662 申请日期 1984.03.20
申请人 FERRER INTERNATIONAL, S.A. 发明人 FOGUET, RAFAEL;ANGLADA, LUIS;RAGA, MANUEL M.;ORTIZ, JOSE A.;SACRISTAEN, AURELIO;CASTELLO, JOSE M.
分类号 C07D295/08;A61K31/34;A61K31/341;A61K31/415;A61P1/04;A61P43/00;C07D233/54;C07D233/64;C07D277/20;C07D277/48;C07D295/096;C07D307/52;(IPC1-7):C07D277/20;C07D211/18 主分类号 C07D295/08
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