发明名称 |
N-cyano-formamidines |
摘要 |
New N-cyano-formamidine are disclosed of the formula I: <IMAGE> I wherein R is 2-[[(5-methyl-1H-Imidazol-4-yl)methyl]thio]ethyl, 2-[[[5-[dimethylamino)methyl]-2-furanyl]methyl]thio]ethyl, 2-[[[2-[(aminoiminomethyl)amino]-4-thiazolyl]methyl]thio]ethyl or 3-[3-(1-piperidinylmethyl)phenoxy]propyl, as well as a process for its production, and pharmaceutical preparations containing the same. The compounds possess histamine-induced gastric acid secretion-inhibiting activity, and are indicated for use in the treatment of peptic ulcer and other pathologies caused or stimulated by gastric acidity.
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申请公布号 |
US4600780(A) |
申请公布日期 |
1986.07.15 |
申请号 |
US19840595662 |
申请日期 |
1984.03.20 |
申请人 |
FERRER INTERNATIONAL, S.A. |
发明人 |
FOGUET, RAFAEL;ANGLADA, LUIS;RAGA, MANUEL M.;ORTIZ, JOSE A.;SACRISTAEN, AURELIO;CASTELLO, JOSE M. |
分类号 |
C07D295/08;A61K31/34;A61K31/341;A61K31/415;A61P1/04;A61P43/00;C07D233/54;C07D233/64;C07D277/20;C07D277/48;C07D295/096;C07D307/52;(IPC1-7):C07D277/20;C07D211/18 |
主分类号 |
C07D295/08 |
代理机构 |
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主权项 |
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地址 |
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