| 摘要 |
FIELD: medicine, pharmaceutics. ^ SUBSTANCE: invention refers to new capmtotecin derivatives of a following structure of formula (I) where R1 represents H, C1-C4alkyl, branched C1-C4alkyl or vinyl, as well as to a pharmaceutical composition exhibiting antineoplastic activity and based on the given compounds, and to application thereof for making a drug for treating tumours. ^ EFFECT: there are produced and described new compounds which exhibit high antineoplastic activities and have good water-solubility; they can be applied for creating new drugs. ^ 7 cl, 3 ex, 3 tbl, 4 dwg |
