Process for removing pesticides from Ginkgo biloba extracts, which involves submitting an extract obtained by conventional methods to the following steps: a. Liquid-liquid extraction of the extract to obtain a medium polarity fraction containing ginkgo terpenes and pesticides not removable with hexane, and a high polarity fraction containing ginkgo flavone glycosides; b. crystallisation from the medium polarity fraction obtained at step a) to give an intermediate with a ginkgolide content of not less than 50%; c. crystallisation from the residual solution obtained at step b) to give an intermediate with a bilobalide content of not less than 50%; d. mixing of the high polarity fraction obtained at step a) with the ginkgo terpene intermediate and the bilobalide intermediate obtained at steps b) and c).
申请公布号
WO2010115566(A3)
申请公布日期
2011.02.10
申请号
WO2010EP02046
申请日期
2010.03.31
申请人
INDENA S.P.A.;GIORI, ANDREA;MOMBELLI, GIACOMO;ARPINI, SABRINA;ACERBI, MARIO
发明人
GIORI, ANDREA;MOMBELLI, GIACOMO;ARPINI, SABRINA;ACERBI, MARIO