发明名称 ISOXAZOLINES AS INHIBITORS OF FATTY ACID AMIDE HYDROLASE
摘要 The present invention provides isoxazoline FAAH inhibitors of the formula (I): or pharmaceutically acceptable forms thereof, wherein each of G, Ra, Rb, Rc, and Rd are as defined herein. The present invention also provides pharmaceutical compositions comprising a compound of formula (I), or a pharmaceutically acceptable form thereof, and a pharmaceutically acceptable excipient. The present invention also provides methods for treating an FAAH-mediated condition comprising administering a therapeutically effective amount of a compound of formula (I), or pharmaceutically acceptable form thereof, to a subject in need thereof.
申请公布号 US2011034437(A1) 申请公布日期 2011.02.10
申请号 US20100782658 申请日期 2010.05.18
申请人 INFINITY PHARMACEUTICALS, INC. 发明人 BEHNKE MARK L.;CASTRO ALFREDO C.;CHAN LAWRENCE K.;EVANS CATHERINE A.;GRENIER LOUIS;GROGAN MICHAEL J.;LEBLANC YVES;LIU TAO;PELUSO STEPHANE;SNYDER DANIEL A.;TIBBITTS THOMAS T.
分类号 A61K31/55;A61K31/42;A61K31/438;A61P1/08;A61P3/00;A61P3/04;A61P9/00;A61P25/00;A61P25/20;A61P25/28;A61P25/30;C07D261/20;C07D498/10 主分类号 A61K31/55
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