On-Chip-Analyse kovalent markierter Probenspezies

摘要

A method for analyzing a sample comprising different sample compounds is described. The method comprises staining the sample compounds by adding a dye species to a solution of the sample, the dye species having reactive groups adapted for forming covalent bonds with specific groups of the sample compounds, and providing the modified sample compounds to a microfluidic chip, the microfluidic chip being adapted to provide an electrophoretic separation. The method further comprises electrophoretically separating the modified sample compounds, and detecting separated compounds.