METHOD OF PREVENTING RENAL DISEASE AND TREATING SYMPTOMS THEREOF

摘要

The invention relates to novel methods of using 2-methylene-19-nor-20(S)-1,25- dihydroxyvitamin D3 to prevent renal disease, particularly Lupus nephritis, in a subject at risk of developing renal disease. Methods of preventing symptoms of renal disease, such as proteinuria, splenomegaly or glomerular damage are also provided. Methods of treating symptoms of renal disease, including proteinuria and splenomegaly, are also provided.