发明名称 PARTICULATE CELL CARRIER AND CELL-INTRODUCING SYSTEM CONTAINING THE SAME AND CELL CULTURE SYSTEM
摘要 <P>PROBLEM TO BE SOLVED: To provide a cell carrier which has a proper size not clogging an injector or a catheter, even when injected through the injector or the catheter, and can stably hold various cells in a living state. <P>SOLUTION: There is provided a particulate cell carrier comprising fine particles comprising low molecular heparin and protamine. The particulate cell carrier easily forms cell aggregates having suitable sizes together with various adhesive cells, and the cell aggregates can be injected into a body with an injector or the like. The particulate cell carrier can be used as a carrier for cell transplantation in regenerative medical treatments. Various cells, especially CD-34 positive hematopoietic system stem cells or mesenchymal stem cells which have been hardly obtained in a sufficient yield with a conventional technique, can be cultured in a serum-free state or in a low concentration serum state (about 1 to 2%) on a substrate coated with the fine particles. <P>COPYRIGHT: (C)2011,JPO&INPIT
申请公布号 JP2011024423(A) 申请公布日期 2011.02.10
申请号 JP20080147231 申请日期 2008.06.04
申请人 ISHIHARA MASAYUKI 发明人 ISHIHARA MASAYUKI;KISHIMOTO SATOKO;NAKAMURA SHINGO;HATTORI HIDEMI;KANETANI YASUHIRO;NANBU MASAKI
分类号 C12N5/07;A61K9/16;A61K45/00;A61K47/36;A61K47/42;A61L27/00;A61P43/00;C12M3/00 主分类号 C12N5/07
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