发明名称 COMPOUND, METHOD AND PHARMACEUTICAL COMPOSITION FOR INHIBITING PARP
摘要 PROBLEM TO BE SOLVED: To provide compounds, compositions and methods for inhibiting PARP activity to treat and/or prevent damage of cells, tissue and/or organs originated from cell damage or cell death caused by, for example, necrosis or apoptosis. SOLUTION: The invention relates to compounds which inhibit poly(ADP-ribose)polymerase ("PARP"), compositions containing these compounds, and methods for using these PARP inhibitors to treat, prevent and/or ameliorate the effects of the conditions specified in the descriptions. COPYRIGHT: (C)2011,JPO&INPIT
申请公布号 JP2011026347(A) 申请公布日期 2011.02.10
申请号 JP20100248858 申请日期 2010.11.05
申请人 EISAI INC 发明人 KALISH VINCENT J;ZHANG JIE;XU WEIZHENG;LI JAMES JIA-HE;XING AMY D
分类号 C07D471/06;A61K;A61K31/495;A61K31/5025;A61K31/519;A61K31/5377;A61K31/675;A61P1/04;A61P3/10;A61P9/00;A61P9/10;A61P13/12;A61P17/00;A61P17/16;A61P19/02;A61P19/06;A61P21/00;A61P21/02;A61P25/00;A61P25/02;A61P25/04;A61P25/24;A61P25/28;A61P27/02;A61P29/00;A61P31/04;A61P31/18;A61P35/00;A61P35/02;A61P37/02;A61P43/00;C07D487/04;C07D487/06;C07D491/04;C07D491/06;C07F9/6561 主分类号 C07D471/06
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