发明名称 SELECTED CGRP ANTAGONISTS, PROCESSES FOR PREPARING THEM AND THEIR USE AS PHARMACEUTICAL COMPOSITIONS
摘要 The present invention relates to the CGRP antagonists of general formula I wherein R1, R2, R3 and R4 are as defined in claim 1, the tautomers, the isomers, the diastereomers, the enantiomers, the hydrates thereof, the mixtures thereof and the salts thereof and the hydrates of the salts thereof, particularly the physiologically acceptable salts thereof with inorganic or organic acids or bases, as well as those compounds of general formula I wherein one or more hydrogen atoms are replaced by deuterium, pharmaceutical compositions containing these compounds, their use and processes for preparing them.
申请公布号 US2011034444(A1) 申请公布日期 2011.02.10
申请号 US20100907771 申请日期 2010.10.19
申请人 BOEHRINGER INGELHEIM INTERNATIONAL GMBH 发明人 MUELLER STEPHAN GEORG;RUDOLF KLAUS;LUSTENBERGER PHILIPP;SCHAENZLE GERHARD;SANTAGOSTINO MARCO;STENKAMP DIRK;ARNDT KIRSTEN;DOODS HENRI
分类号 A61K31/551;A61P1/00;A61P3/10;A61P25/00;A61P25/06;A61P43/00;C07D401/14;C07D413/14 主分类号 A61K31/551
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