发明名称 TRIAZOLIUM SALTS AS PAR1 INHIBITORS, PRODUCTION THEREOF, AND USE AS MEDICAMENTS
摘要 The invention relates to novel compounds of formula I where X, A−, Q1, Q2 Q3, R2, R3, R4, R5, R6, R7, R8 and R9 are each as defined below. The compounds of formula I have antithrombotic activity and inhibit especially protease-activated receptor 1 (PAR1). The invention further relates to a process for preparing the compound of formula I and to the use thereof as a medicament.
申请公布号 US2011034452(A1) 申请公布日期 2011.02.10
申请号 US20100851219 申请日期 2010.08.05
申请人 SANOFI-AVENTIS 发明人 HEINELT UWE;WEHNER VOLKMAR;HERRMANN MATTHIAS;SCHOENAFINGER KARL;STEINHAGEN HENNING
分类号 A61K31/536;A61K31/437;A61K31/5025;A61K31/5377;A61P3/10;A61P7/02;A61P9/00;A61P9/06;A61P9/10;A61P11/00;A61P29/00;A61P35/00;A61P35/04;C07D471/04;C07D487/04 主分类号 A61K31/536
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