| 发明名称 |
NOVEL (PYRROLOQUINOXALINYL) PYRAZINECARBOHYDRAZIDE-OXALIC ACID CO-CRYSTAL FOR TREATMENT OF CANCER AND OTHER DISEASES |
| 摘要 |
A novel co-crystal of N′-(7-fluoropyrrolo[1,2a]quinoxalin-4-yl)pyrazine-2-carbohydrazide with oxalic acid is disclosed. The disclosed oxalic acid co-crystal demonstrates cancer cell growth inhibition and is more bioavailable than the corresponding free base when administered as a suspension.
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| 申请公布号 |
US2011034473(A1) |
申请公布日期 |
2011.02.10 |
| 申请号 |
US20090937245 |
申请日期 |
2009.04.08 |
| 申请人 |
NOVELIX PHARMACEUTICALS, INC. |
发明人 |
BAUER VICTOR J.;O'NEILL MIKE H.;KIDON BARBARA J.;JANSEN BURKHARD |
| 分类号 |
A61K31/4985;A61P35/00;A61P35/02;C07D487/04 |
主分类号 |
A61K31/4985 |
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