发明名称 IMMUNOGLOBULIN FUSION PROTEIN FORMULATIONS
摘要 The present invention provides compositions of Ig fusion proteins, especially compositions including an Ig fusion protein, a bulking agent, a disaccharide, a surfactant, and a buffer. In one aspect, these compositions are stable under long-term storage or at least one freeze/thaw cycle. The invention also provides methods of preparation of the Ig fusion protein compositions. In one aspect, compositions of the invention are lyophilized. In a further aspect, the compositions are lyophilized by a process that includes an annealing step.
申请公布号 US2011033464(A1) 申请公布日期 2011.02.10
申请号 US20100910146 申请日期 2010.10.22
申请人 WYETH 发明人 BARRY ANTHONY;CROWLEY THOMAS;DIXON DANIEL;JUNEAU JENNIFER;KUMAR AJAY;LI LI;LUKSHA NICHOLAS;SHAMASHKIN MICHAEL;SOLEY ERIN;WARNE NICHOLAS;WEBB CHANDRA
分类号 A61K39/395 主分类号 A61K39/395
代理机构 代理人
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