发明名称 |
TARGETS, INCLUDING YAP1, FOR ANTIFUNGAL DRUG DISCOVERY AND THERAPY |
摘要 |
The present invention is based on the discovery of a two organism model system that can be used to identify virulence factors. The system is also useful in the process of drug delivery. More specifically, we have established valid fungal infection in caenorhabditis elegans with an invading pathogen, the yeast Saccharomyces cerevisiae. Because both species are genetic model organisms, the assay can be used to identify host and virulence factors involved in such interactions.
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申请公布号 |
US2011033442(A1) |
申请公布日期 |
2011.02.10 |
申请号 |
US20070517971 |
申请日期 |
2007.12.10 |
申请人 |
WORCESTER POLYTECHNIC INSTITUTE |
发明人 |
RAO REETA PRUSTY;POLITZ SAMUEL MICHAEL |
分类号 |
C07K14/395;A01K67/033;A61K39/395;A61P31/10;C12N1/19 |
主分类号 |
C07K14/395 |
代理机构 |
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代理人 |
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主权项 |
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地址 |
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