| 发明名称 |
HIGHLY PURE PALIPERIDONE OR A PHARMACEUTICALLY ACCEPTABLE SALT THEREOF SUBSTANTIALLY FREE OF KETO IMPURITY |
| 摘要 |
<p>Provided herein is a highly pure paliperidone or a pharmaceutically acceptable salt thereof substantially free of keto impurity, 3-[2-[4-(6-fluoro-1,2-benzisoxazol-3-yl)-1-piperidinyl]ethyl]-2-methyl-7,8-dihydro-6H-pyrido[1,2-a]pyrimidin-4,9-dione, a process for the preparation thereof, and pharmaceutical compositions comprising highly pure paliperidone or a pharmaceutically acceptable salt thereof substantially free of keto impurity.</p> |
| 申请公布号 |
EP2280967(A2) |
申请公布日期 |
2011.02.09 |
| 申请号 |
EP20090724997 |
申请日期 |
2009.03.26 |
| 申请人 |
ACTAVIS GROUP PTC EHF |
发明人 |
BAPAT, UDAY, RAJARAM;JAYAMANI, MUNUSAMY;RAVISARAVANAN, SIVAJI;SODHA, VISHAL, AMRUTLAL;VALGEIRSSON, JON |
| 分类号 |
C07D471/04;A61K31/517;A61P25/18 |
主分类号 |
C07D471/04 |
| 代理机构 |
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代理人 |
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| 地址 |
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