发明名称 |
ANTIGEN-AND-DRUG VEHICLE COMPRISING SYNTHETIC PEPTIDE, AND MUCOSAL VACCINE USING THE SAME |
摘要 |
<p>Disclosed are an antigen-and-drug (AD) vehicle and a mucosal vaccine utilizing a novel synthetic peptide. The antigen-and-drug (AD) vehicle capable of inducing the production of secretory IgA antibodies, which is a complex of a synthetic peptide having the following amino acid sequence: PVHLKRLm (m is 11 to 15 or 16 to 20, e.g., peptide of SEQ. ID. NO: 1) or KnLm (n is 4 to 8 and m is 11 to 20, e.g., peptide of (SEQ. ID. NO: 2 or 3), and a lipid(s). The mucosal vaccines is obtainable by allowing a mucosal-immunity-IgA-inducing amount of an antigen to coexist with, contact, be captured by, or be adsorbed onto the AD vehicle.</p> |
申请公布号 |
EP2281574(A1) |
申请公布日期 |
2011.02.09 |
申请号 |
EP20090728744 |
申请日期 |
2009.03.30 |
申请人 |
THE UNIVERSITY OF TOKUSHIMA |
发明人 |
KIDO, HIROSHI;TAKEI, TSUNETOMO;MIZUNO, DAI |
分类号 |
A61K39/39;A61K39/12;A61P31/00;A61P31/16;A61P37/08;A61P43/00;C07K7/08;C07K14/00 |
主分类号 |
A61K39/39 |
代理机构 |
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代理人 |
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主权项 |
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地址 |
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