| 摘要 |
<p>Helicobacter pylori, one of the most common human pathogens, is associated with the development of human chronic gastritis, peptic ulcers and gastric cancer. The invention relates to a .alpha.1,6-glucan-containing Helicobacter pylori compound comprising the structure of Formula (I): wherein R is a .alpha.-DDHep-3-.alpha.-L-Fuc-3-.beta.-G1cNAc trisaccharide substituted with an .alpha.1,6-glucan linked to an .alpha.1,3-DD-heptan, and wherein the last DD-Hep residue of .alpha.1,3-DD- heptan is capped with .beta.-G1cNAc residue. Compositions comprising the compound, uses of the compound, and antibodies raised against the compound are also described.</p> |
