摘要 |
The present invention relates to the use of a compound of the following formula (I), as an enzyme substrate for the detection of a peptidase activity or as a pH indicator: according to which: Y1 is a peptide, H or an alkyl W1, W2, W3 and W4 are independently H, Br, Cl, F, I, alkyl, alkoxy, thiomethyl, perfluoroalkyl, nitro, cyano, carboxyl (including the esters or amides thereof) or any combination thereof n = 0, 1 or 2 U is N or N+R and V is CZ6 N or N+R or else V is N or N+R and U is CZ6, R is H, alkyl, aralkyl, aryl, alkanoic or alkylsulphonic Z1, Z2, Z3, Z4 and Z5 are independently H, Br, Cl, F, I, alkyl, aryl, alkoxy, perfluoroalkyl, nitro, cyano, carboxyl, sulphonyl, including the carboxyl or sulphonyl esters or amides and salts thereof. |
申请人 |
BIOMERIEUX;FABREGA, OLIVIER;JAMES, ARTHUR;ORENGA, SYLVAIN;PERRY, JOHN;SALWATURA, VINDHYA LAKSHIKA;STANFORTH, STEPHEN |
发明人 |
FABREGA, OLIVIER;JAMES, ARTHUR;ORENGA, SYLVAIN;PERRY, JOHN;SALWATURA, VINDHYA LAKSHIKA;STANFORTH, STEPHEN |