发明名称 |
Process and intermediates for beta-lactam antibiotics |
摘要 |
<p>7 beta -Acylamino-3-trifluoromethylsulfonyloxy-1-carba-3-cephem-4-carbo ylic acid antibiotic compounds, esters and salts thereof, and the corresponding 7-amino and protected 7-amino 1-carbacephalosporins are provided. The 3-trifluoromethylsulfonyloxy-substituted 1-carbacephalosporins also are useful in a process for preparing 3-halo-1-carbacephalosporins which comprises displacing the 3-trifluoromethylsulfonyloxy ester group with halide ion in an aprotic polar solvent.</p> |
申请公布号 |
IE58997(B1) |
申请公布日期 |
1993.12.15 |
申请号 |
IE19860001900 |
申请日期 |
1986.07.16 |
申请人 |
PRESIDENT AND FELLOWS OF HARVARD COLLEGE |
发明人 |
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分类号 |
C07D471/04;B01J23/00;B01J23/46;C07B53/00;C07B61/00;C07D205/08;C07D205/085;C07D263/22;C07D263/24;C07D401/04;C07D405/06;C07D413/04;C07D413/14;C07D463/00;C07F9/653;C07F9/6561;(IPC1-7):C07D463/00 |
主分类号 |
C07D471/04 |
代理机构 |
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代理人 |
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主权项 |
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地址 |
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