发明名称 PYRIDINE DERIVATIVES AND METHODS OF USE THEREOF
摘要 Disclosed herein are pyridine derivatives, or a pharmaceutically acceptable salt, ester, amide, or prodrug thereof, pharmaceutical compositions comprising the same, and methods of modulating the level or activity of HIF in a subject, inhibiting hydroxylation of HIF α in a subject, modulating expression of HIF-regulated genes in a subject, treating an HIF-related disorder in a subject, increasing levels of endogenous EPO in a subject, or treating a disorder in a subject, using the disclosed compounds.
申请公布号 US2011028507(A1) 申请公布日期 2011.02.03
申请号 US20080672785 申请日期 2008.08.08
申请人 CRYSTALGENOMICS, INC. 发明人 KIM SUN NAM;HONG YONG RAE;SHIN DONGKYU;RO SEONGGU;CHO JOONG MYUNG;LEE MI JUNG;CHANG HO JIN
分类号 A61K31/4365;A61K31/4355;A61P1/00;A61P3/00;A61P7/06;A61P9/10;A61P13/12;A61P19/02;A61P25/00;A61P25/08;A61P29/00;A61P31/18;A61P37/06;C07D491/04;C07D513/04;C12N5/00;C12N9/99 主分类号 A61K31/4365
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