发明名称 |
Formulation of radioprotective alpha beta unsaturated aryl sulfones |
摘要 |
A pharmaceutical composition is provided for administration prior to or after exposure to ionizing radiation for reducing toxic effects of the radiation in a subject. An effective amount of the pharmaceutical composition provided comprising an effective amount of at least one radioprotective α, &bgr; unsaturated aryl sulfone, and at least one component selected from the group consisting of a) at least one water soluble polymer in an amount between about 0.5% and about 90% w/v, b) at least one chemically modified cyclodextrin in an amount between about 20% and about 60% w/v, and c) DMA in an amount between about 10% and about 50% w/v.
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申请公布号 |
US2011028504(A1) |
申请公布日期 |
2011.02.03 |
申请号 |
US20060989468 |
申请日期 |
2006.07.28 |
申请人 |
ONCONOVA THERAPEUTICS, INC. |
发明人 |
MANIAR MANOJ;BELL STANLEY C.;BELL JANICE W. |
分类号 |
A61K31/44;A61K31/10;A61K31/192;A61K31/277;A61K31/341;A61P43/00 |
主分类号 |
A61K31/44 |
代理机构 |
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代理人 |
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主权项 |
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地址 |
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