METHOD FOR PRODUCING OPTICALLY ACTIVE 3-SUBSTITUTED GLUTARIC ACID MONOAMIDE
摘要
<p>Disclosed is a method for producing an optically active 3-substituted glutaric acid monoamide by subjecting a prochiral 3-substituted glutaric acid diamide to the action of an enzyme source which asymmetrically hydrolyzes prochiral 3-substituted glutaric acid diamides. By this method, an optically active 3-substituted glutaric acid monoamide, which is useful as an intermediate for a pharmaceutical product, can be produced from an easily available low-cost starting material with high yield.</p>