发明名称 |
Lactose-free non-hygroscopic anhydrous pharmaceutical compositions of descarboethoxyloratadine |
摘要 |
Stable pharmaceutical compositions of descarboethoxyloratadine (DCL), a metabolic derivative of loratadine, for the treatment of allergic rhinitis and other histamine-induced disorders are disclosed. The compositions are formulated to avoid the incompatibility between DCL and reactive excipients such as lactose and other mono- and di-saccharides. Disclosed compositions include lactose-free, non-hygroscopic and anhydrous stable pharmaceutical compositions of DCL. |
申请公布号 |
ZA9800977(B) |
申请公布日期 |
1998.07.30 |
申请号 |
ZA19980000977 |
申请日期 |
1998.02.06 |
申请人 |
SEPRACOR INC. |
发明人 |
MARTIN P. REDMON;STEPHEN A. WALD;HAL T. BUTLER;PAUL D. RUBIN |
分类号 |
C07D401/04;A61K;A61K9/14;A61K9/20;A61K31/395;A61K31/445;A61K31/4545;A61K31/60;A61P11/02;A61P17/04;A61P27/02;A61P27/16;A61P29/00;A61P37/08;A61P43/00 |
主分类号 |
C07D401/04 |
代理机构 |
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代理人 |
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主权项 |
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地址 |
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