| 发明名称 |
Synthetic peptide inhibitors of thrombin and thrombin activation of protease activated receptors 1 and 4 |
| 摘要 |
The invention relates to synthetic peptide analogs of D-Arg-Oic-Pro-Gly-Phe and methods of their use to inhibit human platelet aggregation, thrombosis and cell activation mediated by PAR1 and PAR4.
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| 申请公布号 |
US7879792(B2) |
申请公布日期 |
2011.02.01 |
| 申请号 |
US20050142364 |
申请日期 |
2005.06.02 |
| 申请人 |
THE REGENTS OF THE UNIVERSITY OF MICHIGAN |
发明人 |
SCHMAIER ALVIN H.;MOSBERG HENRY I.;MARQUES FERNANDA F.;HILFINGER JOHN |
| 分类号 |
A61K38/00;A61K38/04;A61K38/36 |
主分类号 |
A61K38/00 |
| 代理机构 |
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