发明名称 ANHYDROUS CRYSTALLINE FORMS OF N-Ý1-(2-ETHOXYETHYL)-5-(N-ETHYL-N-METHYLAMINO)-7-(4-METHYLPYRIDIN-2-YL-AMINO)-1H-PYRAZOLO[4,3-D]PYRIMIDINE-3-CARBONYL¨METHANESULFONAMIDE
摘要 The invention comprises (1) anhydrous crystalline forms of N-[1-(2-ethoxyethyl)-5-(N-ethyl-N-methylamino)-7-(4-methylpyridin-2-yl-amino)-1H-pyrazolo[4,3-d]pyrimidine-3-carbonyl]methanesulfonamide, (2) pharmaceutical compositions comprising at least one such form, (3) methods for the treatment of a phosphodiesterase-5-mediated condition using at least one such form, and (4) methods for preparing such forms. The compound N-[1-(2-ethoxyethyl)-5-(N-ethyl-N-methylamino)-7-(4-methylpyridin-2-yl-amino)-1H-pyrazolo[4,3-d]pyrimidine-3-carbonyl]methanesulfonamide has the following structure (I).
申请公布号 PT1881985(E) 申请公布日期 2011.02.01
申请号 PT20060744689T 申请日期 2006.05.03
申请人 PFIZER, INC. 发明人 STEFAN COLIN JOHN TAYLOR;DAVID ANDREW ENTWISTLE;PETER VALLANCE MARSHALL
分类号 C07D487/04;A61K31/519;A61P9/12 主分类号 C07D487/04
代理机构 代理人
主权项
地址