CELL BASED SENSOR WITH OPTICAL OBSERVATION OF CELL CAPACITY BY REAL TIME, PREPARATION METHOD THEREOF AND MULTIANALYTE-DETECTABLE SENSOR CHIP USING THE SAME

摘要

PURPOSE: A transparent cell based sensor for real-time optical observation of cell capacity, a manufacturing method thereof and a multi-detection sensor chip using the same are provided to optically observe the movement of cell in real time and improve the reliability of detection by detecting signals generated from the transparent cell based sensor with an electro-chemical method. CONSTITUTION: A transparent cell based sensor for real-time optical observation of cell capacity comprises an ion selective field effect transistor type sensor(150,160) and an electro-chemical sensor(140) which are formed in parallel to each other on a transparent substrate. Each sensor comprises a transparent drain electrode, a source electrode, a transparent semiconductor layer, a transparent ion sensitivity insulator detection layer and a reference electrode.