| 发明名称 |
TWEAK RECEPTOR |
| 摘要 |
The present invention provides the TWEAK receptor and methods for identifying and using agonists and antagonists of the TWEAK receptor. In particular, the invention provides methods of screening for agonists and antagonists and for treating diseases or conditions mediated by angiogenesis, such as solid tumors and vascular deficiencies of cardiac or peripheral tissue.
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| 申请公布号 |
US2011020267(A1) |
申请公布日期 |
2011.01.27 |
| 申请号 |
US20100899397 |
申请日期 |
2010.10.06 |
| 申请人 |
IMMUNEX CORPORATION |
发明人 |
KIM KRISTINE M.;WILEY STEVEN R.;KETCHEM RANDAL R.;FANSLOW, III WILLIAM C. |
| 分类号 |
A61K39/395;G01N33/50;A61K31/7088;A61K38/00;A61K38/17;A61K38/19;A61K38/20;A61K38/21;A61K45/00;A61K48/00;A61P9/00;A61P9/10;A61P9/14;A61P17/02;A61P35/00;A61P35/02;A61P37/06;C07K14/705;C07K14/715;C07K16/28;C12N1/15;C12N1/19;C12N1/21;C12N5/10;C12N15/09;C12P21/02;C12Q1/02;G01N33/15;G01N33/53;G01N33/566 |
主分类号 |
A61K39/395 |
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