| 摘要 |
PURPOSE: A method for obtaining free iodine in preparation of aqueous iodine chloride by adding potassium iodide is provided to produce free iodine which is used for synthesizing non-ionic X-ray contrast medium. CONSTITUTION: In reactor, iodine, hydrochloric acid, water, and sodium chloride are mixed in 20°C. Aqueous sodium chlorate solution is added to 3 to 4 hours in the reactor. The mixture and the sodium chlorate aqueous solution are mixed at least more than 10 hours in 50°C. A reactive sample is extracted under the presence of the hydrochloric acid into the dichloromethane. A small amount of potassium iodide is added. After adding less than 15kg iodination potassium, the free iodine is produced. |
