| 发明名称 |
TAMPER-RESISTANT DOSAGE FORM FOR OXIDATION-SENSITIVE OPLOIDS |
| 摘要 |
<p>The invention relates to a thermoformed pharmaceutical dosage form having a breaking strength of at least 300 N, said dosage form comprising - an opioid (A), - - a free physiologically acceptable acid (B) in an amount of from 0T001 to 5.0 wt.-%, based on the total weight of the pharmaceutical dosage form, and - a polyalkylene oxide (C) having a weight average molecular weight Mw of at least 200,000 g/mol.</p> |
| 申请公布号 |
WO2011009603(A1) |
申请公布日期 |
2011.01.27 |
| 申请号 |
WO2010EP04460 |
申请日期 |
2010.07.21 |
| 申请人 |
GRUENENTHAL GMBH;BARTHOLOMAEUS, JOHANNES;GEISSLER, ANJA;BERTRAM, ULRIKE;GRIESSMANN, KORNELIA |
发明人 |
BARTHOLOMAEUS, JOHANNES;GEISSLER, ANJA;BERTRAM, ULRIKE;GRIESSMANN, KORNELIA |
| 分类号 |
A61K9/20;A61K9/28;A61K31/485 |
主分类号 |
A61K9/20 |
| 代理机构 |
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