A MULTICOMPONENT MAGNETIC NANOPARTICLE DELIVERY SYSTEM FOR LOCAL DELIVERY TO HEART VALVE LEAFLETS AND OTHER ANIMAL TISSUES

摘要

The invention features devices, systems, and methods for targeted delivery of therapeutic agents in magnetic particle carriers to desired locations on tissue in the body. The systems and methods utilize at least one device comprising a source of magnetization, and at least one device comprising a magnetic or magnetizable material, to facilitate close tissue apposition and sealing, and to facilitate site-specific delivery of magnetic particles comprising therapeutic agents.