| 摘要 |
An integrated magnetic field generation and detection platform is described that is capable of manipulating and detecting individual magnetic particles, such as spherical super-paramagnetic beads, and providing biosensing functionality. The platform is implemented in an integrated circuit, a portion of the surface of which is functionalized with one or more biochemical agents that binds tightly (i.e., specifically) with a target analyte. The magnetic beads are similarly functionalized with one or more biochemical agents that that bind specifically with the target analyte. When a sample is introduced, magnetic beads that specifically bind to the integrated circuit can be separated from non-specifically bound beads and detected.
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