Disclosed are isoform selective Phospholipase D inhibitors. In one aspect, the disclosed compounds can have a structure represented by a formula (I): Also disclosed are methods of making and using the compounds. Also disclosed are pharmaceutical compositions and kits comprising the compounds. This abstract is intended as a scanning tool for purposes of searching in the particular art and is not intended to be limiting of the present invention.
申请公布号
WO2011011680(A1)
申请公布日期
2011.01.27
申请号
WO2010US43045
申请日期
2010.07.23
申请人
VANDERBILT UNIVERSITY;BROWN, H., ALEX;LINDSLEY, CRAIG, W.;WATERSON, ALEX, G.;SCOTT, SARAH, A.
发明人
BROWN, H., ALEX;LINDSLEY, CRAIG, W.;WATERSON, ALEX, G.;SCOTT, SARAH, A.