| 摘要 |
<p>A process for the preparation of fluconazole, which is a well blown antifungal agent, and of pharmaceutically acceptable salts thereof is disclosed, wherein a novel compound of the formula (IV) <CHEM> wherein R represents H, benzyl, triphenylmethyl and COOR<1> with R<1> being alkyl or aryl, preferably tert-butyl or ethyl, and Z represents a triazole radical or hydrazine radical optionally substituted by R being defined as above, optionally in the salt form, is reacted with s-triazine. The novel compound (IV) is an object of the invention as well. <IMAGE></p> |
