发明名称 |
Crystallization Inhibitor and Its Use in Gelatin Capsules |
摘要 |
The present invention describes soft gelatin capsules that encapsulate a water-insoluble active ingredient and an excipient composed of a crystallization inhibitor that stabilizes the water-insoluble inhibitor. The crystallization inhibitor being at least one mononacylglycerol compound whose acyl group is a fatty acid residue of 6-18 carbon atoms. The capsule contents are more resistant to turbidity, forming a coarse emulsion, and crystallization of the active ingredient compared with compositions absent the crystallization inhibitor.
|
申请公布号 |
US2011020438(A1) |
申请公布日期 |
2011.01.27 |
申请号 |
US20060886500 |
申请日期 |
2006.03.16 |
申请人 |
IVAX PHARMACEUTICALS S.R.O. |
发明人 |
ANDRYSEK TOMAS;VRANA ALES |
分类号 |
A61K9/48;A61K31/436;A61K38/13;A61P37/00;B65B3/04 |
主分类号 |
A61K9/48 |
代理机构 |
|
代理人 |
|
主权项 |
|
地址 |
|