发明名称 |
TARGETED BINDING AGENTS DIRECTED TO PDGRF-ALPHA AND USES THEREOF |
摘要 |
Targeted binding agents directed to the antigen PDGFR-alpha and uses of such agents are disclosed herein. More specifically the invention relates to fully human monoclonal antibodies directed to the antigen PDGFR-alpha and uses of these antibodies. Aspects of the invention also relate to hybridomas or other cell lines expressing such antibodies. The described targeted binding agents and antibodies are useful as diagnostics and for the treatment of diseases associated with the activity and/or overexpression of PDGFR-alpha.
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申请公布号 |
US2011020360(A1) |
申请公布日期 |
2011.01.27 |
申请号 |
US20100708022 |
申请日期 |
2010.02.18 |
申请人 |
ASTRAZENECA AB |
发明人 |
LAING NAOMI;KANG JASPAL SINGH;FOLTZ IAN;GAZIT-BOMSTEIN GADI;YANG XIAO-DANG;CARTLIDGE SUE A.;BLAKEY DAVID CHARLES |
分类号 |
A61K39/395;A61K39/44;A61P35/00;C07H21/04;C07K16/00;C12N5/10;C12N15/63 |
主分类号 |
A61K39/395 |
代理机构 |
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代理人 |
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主权项 |
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地址 |
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