发明名称 |
Methods and Compositions for Detecting Amyotrophic Lateral Sclerosis |
摘要 |
The invention provides binding proteins that bind to misfolded or monomeric SOD1, and not to native homodimeric SOD1. The invention also includes methods of diagnosing, detecting or monitoring amyotrophic lateral sclerosis in a subject. In addition, the invention provides methods of identifying substances for the treatment or prevention of amyotrophic lateral sclerosis and kits using the binding proteins of the invention.
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申请公布号 |
US2011020358(A1) |
申请公布日期 |
2011.01.27 |
申请号 |
US20100840708 |
申请日期 |
2010.07.21 |
申请人 |
AMORFIX LIFE SCIENCES LTD.;UNIVERSITY HEALTH NETWORK |
发明人 |
CHAKRABARTTY AVIJIT;RAKHIT RISHI;CASHMAN NEIL R. |
分类号 |
A61K39/395;C07K7/06;C07K7/08;C07K16/00;G01N33/566 |
主分类号 |
A61K39/395 |
代理机构 |
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代理人 |
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主权项 |
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地址 |
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