发明名称 |
TARGETED SYNTHETIC NANOCARRIERS WITH PH SENSITIVE RELEASE OF IMMUNOMODULATORY AGENTS |
摘要 |
This invention relates to compositions, and related methods, of synthetic nanocarriers that target sites of action in cells, such as antigen presenting cells (APCs), and comprise immunomodulatory agents that dissociate from the synthetic nanocarriers in a pH sensitive manner. Also disclosed are compositions and methods relating to synthetic nanocarriers that encapsulate labile immunomodulatory agents that dissociate from the synthetic nanocarriers in a pH sensitive manner.
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申请公布号 |
US2011020388(A1) |
申请公布日期 |
2011.01.27 |
申请号 |
US20100788260 |
申请日期 |
2010.05.26 |
申请人 |
SELECTA BIOSCIENCES, INC. |
发明人 |
ZEPP CHARLES;GAO YUN;KEEGAN MARK J.;BALDWIN SAM;FU FEN-NI;JOHNSTON LLOYD;LIPFORD GRAYSON B. |
分类号 |
A61K39/385;A61P37/02;C07D471/04;C07D473/34;C07H21/00 |
主分类号 |
A61K39/385 |
代理机构 |
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代理人 |
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主权项 |
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地址 |
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