摘要 |
FIELD: medicine, pharmaceutics. ^ SUBSTANCE: invention relates to novel substituted derivatives of urea, which possess properties of selective modulator of cardiac sarcomere, for instance, enhance action of cardiac myosin. Novel compounds are selected from compounds corresponding to structural formulas: . ^ EFFECT: compounds can be used in treatment for heart failure, in particular in treatment of systolic heart failure and congestive heart failure. ^ 30 cl, 17 ex |