发明名称 COMPOUNDS, COMPOSITIONS AND METHODS OF THEIR APPLICATION
摘要 FIELD: medicine, pharmaceutics. ^ SUBSTANCE: invention relates to novel substituted derivatives of urea, which possess properties of selective modulator of cardiac sarcomere, for instance, enhance action of cardiac myosin. Novel compounds are selected from compounds corresponding to structural formulas: . ^ EFFECT: compounds can be used in treatment for heart failure, in particular in treatment of systolic heart failure and congestive heart failure. ^ 30 cl, 17 ex
申请公布号 RU2410384(C2) 申请公布日期 2011.01.27
申请号 RU20070101619 申请日期 2005.06.16
申请人 TSITOKINETIKS, INK. 发明人 MORGAN BREHDLI P.;MUTSI ALEKS;LJU PU-PING;KREJNEK EHRIKA;TOKHIMOTO TODD;MORGANS DEHVID
分类号 A61K31/496;A61P9/04;C07D401/12 主分类号 A61K31/496
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