| 发明名称 |
METHODS OF SUPPRESSING MICROGLIAL ACTIVATION |
| 摘要 |
Methods of suppressing the activation of microglial cells in the Central Nervous System (CNS), methods of ameliorating or treating the neurological effects of cerebral ischemia or cerebral inflammation, and methods of combating specific diseases that affect the CNS by administering a compound that binds to microglial receptors and prevents or reduces microglial activation are described. Also described are methods of screening compounds for the ability to suppress or reduce microglial activation.
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| 申请公布号 |
US2011021413(A1) |
申请公布日期 |
2011.01.27 |
| 申请号 |
US20100779725 |
申请日期 |
2010.05.13 |
| 申请人 |
LASKOWITZ DANIEL T;MATTHEW WILLIAM D;MCMILLIAN MICHAEL |
发明人 |
LASKOWITZ DANIEL T.;MATTHEW WILLIAM D.;MCMILLIAN MICHAEL |
| 分类号 |
A61K38/16;A61K45/00;A61B;A61B1/00;A61K31/13;A61K31/19;A61K31/197;A61K31/428;A61K31/515;A61K31/52;A61K31/53;A61K31/55;A61K38/00;A61K38/04;A61K38/08;A61K38/10;A61K38/17;A61K38/18;A61K38/19;A61K38/20;A61K38/21;A61K39/02;A61K39/12;A61K39/395;A61P9/10;A61P21/02;A61P23/00;A61P25/00;A61P25/04;A61P25/14;A61P25/16;A61P25/18;A61P25/28;A61P25/30;A61P29/00;A61P31/00;A61P43/00;C07K14/47;C07K14/775;C12N5/00;C12N5/02;C12N7/00;C12N7/01;C12Q1/68;G01N33/50;G01N33/92 |
主分类号 |
A61K38/16 |
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